Fertility Treatment - GynaeMD Infertility Clinic

In-Vitro Fertilisation (IVF)

What Is IVF (In-Vitro Fertilisation)?

In-Vitro Fertilisation, widely known as IVF, is the technique in which the egg and sperm are fertilised together outside the woman’s womb in a laboratory. It can be divided into 4 different stages.

IVF Singapore

What Are the Four Stages of IVF (In-Vitro Fertilisation)?

Stage 1: Ovarian Stimulation


Daily fertility hormonal injections are administered to the female partner for a 10 to 12-day period on average. This is to increase the number of eggs maturing in the ovary. Ultrasound scans and blood tests are done every few days to assess the growth and quantity of the eggs. The dose of the hormonal injections may be adjusted to ensure optimal growth of the eggs.

Stage 2: Egg Collection


Using a special needle attached to an ultrasound probe, our gynaecologist will collect eggs from the ovaries trans-vaginally. The female patient will be sedated during the procedure to minimise any discomfort.

Stage 3: Fertilisation


At the time of the egg collection, the male patient is required to produce fresh semen. To ensure good sperm quality, he is advised to abstain from sexual intercourse 3 days before the procedure. The healthiest sperms are selected and carefully prepared for fertilisation of the eggs. Intra-Cytoplasmic Sperm Injection (ICSI) is used to increase the number of fertilised embryos available for embryo transfer and involves injecting a single sperm into each egg via a microneedle.

Stage 4: Embryo Transfer


The embryos will be closely monitored by an embryologist for the next few days, before selecting the most suitable ones for embryo transfer. A maximum of 2 embryos can be transferred into the uterus using a fine catheter. Any extra good quality embryos will be frozen and stored for future use. The female patient will be given daily hormonal support to improve the chances of embryo implantation and ultimately pregnancy. A pregnancy test is then performed 14 to 17 days after the embryo transfer.

Who Is Suitable for IVF Treatment?

The IVF procedure is the only available fertility treatment for women with irreparably-damaged or blocked fallopian tubes. It is also recommended for couples with conditions like endometriosis, ovulatory dysfunction, unexplained infertility, failed SOIUI and sperm disorders.

Gynaecologists may also recommend the IVF procedure for women over the age of 40 who experience reduced fertility, low ovarian reserve, or polycystic ovarian syndrome (PCOS). Individuals who have undergone tubal ligation (female sterilisation) or a vasectomy (male sterilisation) may require IVF to conceive. Couples unable to conceive after six months (above 35 years old) to a year (below 35 years old) of trying or those with a known genetic disorder who want to avoid passing it on may also consider IVF.

The entire IVF procedure needs to be properly adhered to so it requires close monitoring. Couples are required to undergo a detailed consultation with our gynaecologist before treatment can commence. Initial consultations will involve blood tests and health screenings for infectious diseases, semen analysis and ovarian reserve testing to ensure suitability for the treatment.

Our IVF doctor will be delighted to answer any of your questions regarding the entire IVF process during your consultation. This will provide you with a more thorough understanding of what to expect and help to reduce patient anxiety when you realise that modern IVF treatments are now relatively stress-free.

How to Prepare for IVF (In-Vitro Fertilisation)

Once a couple is deemed eligible for an IVF procedure in Singapore, the gynaecologist will discuss the details of the IVF process and recommend several pre-treatment tests and preparatory measures.

Women may undergo ovarian reserve testing which involves a blood test and a vaginal ultrasound to assess the number of eggs remaining in a woman’s ovaries and predict how well she may respond to fertility medications. The inner lining of the uterus may also be examined via a hysteroscopy. In this test, an illuminated hysteroscope is inserted through the vagina and cervix into the uterus.

Our staff will also instruct and supervise the female partner on how to properly inject herself with daily hormonal injections which stimulate the ovaries to produce multiple eggs. Patients are typically advised to start taking folic acid supplements at least one month before the embryo transfer and for the first three months of the pregnancy to reduce the risk of miscarriage.

What to Expect After an IVF Procedure

After the embryo transfer, patients can generally get back to their regular daily routine with some precautionary advice. A pregnancy blood test is then performed 14–17 days after the embryo transfer to measure beta HCG (human chorionic gonadotropin) levels which is a hormone released by the placenta during pregnancy.

If the pregnancy test result is positive, the patient will continue her antenatal care at our clinic. However, if the pregnancy test yields a negative result, the gynaecologist will determine if the treatment protocols need to be modified before commencing the next IVF cycle.

IVF Treatment Success Rates in Singapore

At our fertility clinic, the success rates for IVF-ICSI treatments vary according to various infertility factors such as the patient’s age (females in particular), the quality of eggs and sperm, the duration of infertility, and the general state of health of the couple. Generally, a higher success rate is expected for women below the age of 35.

Other factors that affect IVF success rates include a history of past pregnancies and/or number of IVF cycles and any underlying medical conditions. Additionally, certain lifestyle factors like smoking, alcohol consumption, obesity and stress may reduce the chances of conceiving through IVF.

What Are the Risks Associated with IVF Treatment?

IVF treatment is considered a safe procedure with most patients experiencing no adverse effects on their health or pregnancy. Nonetheless, it is important to be aware of potential risks associated with IVF treatment, including:

  • Multiple Pregnancies – Transferring more than one embryo into the uterus can lead to multiple pregnancies, which may increase the risk of premature labour and low birth weight.
  • Ectopic Pregnancy – This occurs when a fertilised egg implants outside the uterus, such as in the fallopian tubes.
  • Egg Retrieval Complications – The process of egg retrieval carries potential risks of bleeding, infection, or damage to nearby organs.
  • Ovarian Hyperstimulation Syndrome (OHSS) – This condition occurs when the ovaries become enlarged and fluid accumulates in the abdomen due to an exaggerated response to fertility medications.

What Are the Side Effects of IVF Treatment?

Some patients may experience the following side effects following IVF treatment:

  • Breast tenderness and enlargement due to high oestrogen levels
  • Abdominal bloating
  • Mild cramping
  • Constipation
  • Hot flashes
  • Bruising and soreness around the injection sites during ovarian stimulation
  • Clear or bloody vaginal discharge

Why Choose Our Clinic for IVF Treatment?

Our IVF clinic offers comprehensive fertility assessments and personalised treatment plans in a supportive environment to help couples fulfil their desire of starting a family. For enquiries about our IVF services or to schedule a consultation with our specialist, Dr Christopher Ng, please contact us at 6733 8810 today.

FAQs About IVF (In-Vitro Fertilisation)

  • Is the IVF procedure painful?

    That depends on which stage of the IVF treatment one is at. Certain stages such as the self-injections tend to be painless but egg retrieval process may be slightly uncomfortable which is why our patients are sedated for this procedure.

  • How much does IVF cost in Singapore?

    The cost of an IVF procedure in Singapore can vary depending on hospital fees, gynaecologist fees, medications, ultrasound scans or laboratory tests, as well as any additional tests and treatments required along the way.

  • How long does the IVF process take from beginning to end?

    The entire IVF cycle, from the initial consultation to the embryo transfer, usually takes approximately 5–7 weeks to complete.

  • How many IVF cycles do people need?

    A single IVF cycle usually produces multiple embryos, enough for an average of two to four transfers. If the first transfer is unsuccessful, the remaining embryos can be used for the next transfer. There is no limit to the number of IVF cycles needed to conceive as it depends on the determination of the couple and their financial budget.

  • How long does it take to become pregnant after IVF?

    Pregnancy is not a guarantee. That said, pregnancy testing usually takes place around 14-17 days following embryo transfer.

  • Can you select the gender during IVF?

    No, gender selection during IVF is not allowed in Singapore. This option is only allowed for patients with a family history of a sex-linked chromosomal disorder.

  • How soon after a failed IVF procedure can you try again?

    If an IVF cycle is unsuccessful, patients usually wait 1 month before they commence the next cycle

Fertility Doctor - Dr Christopher Ng

Our IVF Gynaecologist

Dr Christopher Ng
Consultant Obstetrician & Gynaecologist
MBBS (Imperial College, UK), MMed (O&G) (S’pore),
FRANZCOG (Aust-NZ), FAMS (O&G) (S’pore)

Dr Christopher Ng is an obstetrician and gynaecologist in Singapore with over 20 years of experience. He is proficient in the management of fertility problems and offers a wide range of fertility treatments ranging from infertility assessment to assisted reproductive technologies (ART) such as IVF and SOIUI. With a patient-centric approach, Dr Ng is committed to helping his patients achieve their goal of parenthood.

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